This drama is set in a south Florida plastic surgery center, McNamara-Troy, centering around the two doctors who own it. Sean McNamara (Dylan Walsh) is having problems at home, trying to keep his family together, trying to patch up the rocky road him and his wife Julia (Joely Richardson) are experiencing. On the other hand, sex-craved Christian Troy (Julian McMahon) uses his charm to bring in potential female candidates and conducts shady business deals, often for the love of money. While Sean takes his job seriously, he often has to fix Christian's mistakes. During the first season, Sean and Christian got mixed up with Escobar Gallardo, a Colombian drug lord who forced the two to do free surgery whenever he wanted them to. Sean's marriage with Julia began to wear thin, and Sean had an affair with a patient named Megan O'Hara. Julia went back to school, but it was interrupted by a miscarriage of a child Sean and Julia were trying to have. Christian learned he is the father of a baby with a woman named Gina, who he met at Sexaholics Anonymous. When the baby was born, we learn that the baby is African-American, and therefore not his. Julia questions Matt's paternity.
F.R.I.E.N.D.S.中的Phoebe试图东山再起，不知为什么仅一季度就被东家HBO砍了。 sonychen 注
4400人被未来世界的人带走又送回来，一年后，世界发生了巨大的变化。科利尔已经关掉了Arcadia Estates ，还有他的住宅，为这4400人建起了避难所，同时准备开“4400人中心”，在这儿，其他人可以深入到这4400人当中，自己去发掘4400人的奥秘。 世人对4400人甚感好奇，于是关于他们的神秘能力的流言四处传播，公众态度分为两种，一种是包容他们，一种是畏惧他们。当4400人努力重新开始他们“被打断的生活”时，每个人都会在即将发生的事件中扮演关键角色…那些决定人类命运的事件。
这是一部专门从“骨头”上寻找破案线索的刑侦剧。女博士布莱南绰号“骨头”（艾米丽·丹斯切尔 Emily Deschanel 饰），是个学识渊博、专业素养完美的魅力女性，身上最大特点是“理智”，她最不相信的就是感觉，面对任何事都要讲求逻辑和事实，甚至在人际关系上也一样。幸好她有一个对她非常了解的搭档、警探瑟利·布斯（大卫·伯伦纳兹 David Boreanaz 饰），他体格完美，为人开朗风趣，交流能力一流，在查案过程中经常帮“骨头”打圆场，身上又有“骨头”最欣赏的品质——敬业，勇敢。加上美女图形处理师安吉拉（Michaela Conlin 饰）、碎屑分析家哈吉斯（T.J. Thyne 饰）、DNA分析员扎克（Eric Millegan 饰），几人组成专门性刑侦小组，告诉你关于枯骨的一切，
